You only get one shot, do not miss your chance to blow this opportunity comes once in a lifetime, yo. —Eminem

“Researchers have long sought a one-and-done treatment for hemophilia: If they could fix this mutation by delivering a healthy version of the F9 gene, they could get the body to start making the protein again. ‘Instead of giving 100 to 150 injections per year, an individual would be able to receive one injection, and hopefully that will last indefinitely … I’m a little hesitant to say a lifetime, but that’s what we’re hoping for.'” Welcome to the age of the one-shot cure. It’s miraculous. But miracles don’t come cheap, and these shots can cost several million a pop. Wired: The Era of One-Shot, Multimillion-Dollar Genetic Cures Is Here.