Off Script: “The patient — a mechanic who was a husband and father of two — had been born with a particularly sinister gene mutation that should have doomed him to dementia before his 50th birthday. Instead, his life had been one of remarkable resilience, bucking the script written in his genes.” WaPo (Gift Article): He defied Alzheimer’s for two decades. Scientists want to know how.

+ Sweet Surrender: “People should reduce the sweetness of the diet altogether, starting early in life.” Don’t use sugar substitutes for weight loss, World Health Organization advises.

+ Succession: NYT: The Greatest Wealth Transfer in History Is Here, With Familiar (Rich) Winners. Plus, a conversation with Matthew Desmond: The War on Poverty Is Over. Rich People Won.

+ Erdogan For the Books: “Elon Musk, a self-described ‘free speech absolutist, agreed to censor Twitter in Turkey on Saturday, the day before a critical election.” And every little bit helps. Turkey will hold a runoff election on May 28, with Erdogan in the lead.

+ One Last Fold: “As he detailed in his memoir, ‘The Godfather of Poker,’ Brunson saw poker grow from illegal games in Texas backrooms, with players often shunned by society, to nationally televised broadcasts that made players, including Brunson, into celebrities” Poker legend Doyle Brunson dies at 89.

+ Hurt So Good: NYT (Gift Article) takes you Inside the Last Old-School Seltzer Shop in New York. “Good seltzer should hurt — it should be carbonated enough that it kind of stings the back of your throat.” Speaking of Seltzer, it’s always a good time to look back at a scene from Taxi.