“At 65, she’d needed to have her hip replaced. Because it had not caused her pain, she had not noticed anything was amiss until it was severely degenerated. Cuts, burns, fractures — these did not hurt either. In fact, it often took the smell of burning flesh or her husband identifying blood for her to notice something wrong. She also reported that eating Scotch bonnet chili peppers left only a ‘pleasant glow.'” NYT: At 71, She’s Never Felt Pain or Anxiety. Now Scientists Know Why. (Can her gene mutation lead us to better ways for the rest of us to combat pain?)